![]() ![]() A breast biopsy should not hurt, although it is common to experience soreness, swelling or bruising after a biopsy. We provide a local anesthetic to the area that is being biopsied. If the biopsy reveals a cancerous mass, Solis Mammography will immediately communicate the results to your referring physician so that you may begin treatment planning. A breast biopsy is one of the most definitive ways of evaluating whether or not an abnormality is cancerous. Roughly 30-35% of all biopsies that Solis Mammography performs result in a cancer diagnosis, although the majority of all breast lumps turn out to be benign (non-cancerous). What are the chances that a breast biopsy finds cancer? Solis Mammography will work with you and your physician to create a follow-up plan that is best for you. If cancer cells are not found, some follow up may still be required. The results of a biopsy are delivered by a patient’s physician or a Solis Mammography radiologist depending on the preference of your physician. Once a biopsy is complete, the sample of tissue that has been collected is sent to a laboratory to be analyzed under a microscope by a pathologist to determine whether it is cancerous or not. Stereotactic BiopsyĪ stereotactic breast biopsy uses mammography image-guidance to target the area of concern and help guide the biopsy needle to a specific location. ![]() Ultrasound-Guided BiopsyĪfter placing an ultrasound probe over the area of concern and using local anesthesia, the radiologist guides a biopsy needle directly into the tissue area of interest for sampling. Both are extremely reliable, highly-accurate and non-surgical methods for analyzing breast tissue. ![]() Results are sent to a patient’s physician as soon as they are received from the pathologist. The radiologist will perform the type of breast biopsy she/he feels is necessary to collect an appropriately-sized sample for the pathologist to analyze based upon the size or suspected type of lesion in the breast. During a biopsy, a small sample of tissue is collected from the breast and examined in a pathology lab to determine if it is cancerous or not. Furthermore, by using novel multiplane optical elements, SOLIS can record at rates in the kilohertz regime, while still providing optically-sectioned volumetric imaging.A breast biopsy is recommended when a radiologist identifies a suspicious area in the breast tissue. To align the focal plane of the objective with the illumination plane, SOLIS uses a dedicated optical system downstream from the objective, and hidden from the user, to effectively “tilt” the sample volume so it can be recorded by a camera without optical aberrations.Īs only a single objective is near the sample, the NA of the collection objective in SOLIS can be much larger than in conventional LSM, thus increasing achievable resolution by 15% and photon collection efficiency by over 30%. SOLIS is thus fully compatible with conventional sample mounting. In SOLIS, a high-performance objective with large numerical aperture (NA) is used for generation of a scannable light-sheet and, in stark contrast to conventional LSM, this same objective is used for collection of the sample’s fluorescence signal. Crucially though, the requirement of two objective lenses near the sample has the tremendous drawback of obstructing conventional sample mounting techniques and has hence severely hindered a more widespread use of LSM. Scanning the sample through the imaged plane enables optically sectioned volumetric microscopy. The first objective produces a thin sheet of light that only excites fluorophores within the focal plane of the second objective, thus avoiding the generation of out-of-focus light. It uses two objective lenses oriented at right angles to each other, instead of the single objective used in conventional microscopy. ![]() Light-sheet microscopy (LSM) may be a solution. Yet, many studies rely on 2D imaging or 3D confocal microscopy, which has limited live-cell compatibility due to low imaging speed and high phototoxicity. Fluorescence microscopy of cellular processes should thus be performed in cells residing in their native environment. Biology happens in 3D, in living organisms. ![]()
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